The following abstracts were submitted for consideration in response to the call for abstracts of the 45th EMC. It was the intention of the organizers to cover a wide range of topics focusing on muscle development and function, both in physiology and pathology.
The sessions were chaired by international and French top scientists in those fields who introduced the sessions. The abstracts were reviewed by an independent Abstracts Committee, members or the ISB and the organizers, who also edited the abstracts. Acknowledgments We are grateful to the participants and the speakers who accepted our invitation to contribute with their work to create an excellent platform to discuss the latest achievements in muscle research and to initiate new collaborations.
Patients with chronic heart failure CHF , with either reduced HFrEF or preserved ejection fraction HFpEF are characterized by breathlessness, muscle weakness, and exercise intolerance, the latter being one of the most powerful predictors of prognosis.
The pathophysiology and the molecular changes underlying these symptoms are complex and only partly understood. With respect to treatment, exercise training is one best option and validated in several experimental and human studies.
During the last years our knowledge with respect to molecular changes elicited by exercise training in the skeletal muscle and the diaphragm has increased.
