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This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4. This research investigates the gender-specific associations of uroguanylin levels with various health-related parameters in Iraqi adults. The results revealed significant differences between genders in food style preferences and waist circumference WC risk.
Notably, uroguanylin exhibited distinct correlations with low density lipoprotein LDL cholesterol, glycated hemoglobin HbA1c , body mass index BMI , and WC in females and males, indicating potential gender-specific effects on lipid metabolism, glucose regulation, and adiposity. A total of Iraqi adults 73 females and 67 males were recruited into the study. Physical activity levels, food style preferences, WC risk, and BMI subgroups, were compared between genders.
Significant gender differences were observed in food style preferences, with a higher proportion of males preferring fast food, with a greater percentage of females classified as having a high risk, females exhibited lower height and weight compared to males.
HbA1c levels were significantly lower in females, whereas high density lipoprotein HDL cholesterol levels were significantly higher in females than in males. Uroguanylin concentrations were also significantly lower in females compared to males. Uroguanylin shows a moderately negative correlation with LDL cholesterol in females but not in males. Furthermore, a strong negative association between uroguanylin and HbA1c in females indicated improved glycemic control with higher uroguanylin levels, whereas an opposite trend was observed in males.
